An assessment of growth hormone provocation tests.

An assessment of growth hormone provocation tests.

There are a number of tests available for assessment of anterior pituitary hormone function. Recent concern has centred on the use of provocative tests for growth hormone release and in particular the glucagon and insulin induced hypoglycaemia or insulin tolerance test (ITT). These tests have been associated with cerebral oedema and death of at least two children and, as a result, questions hav...

Growth hormone (GH) provocation tests and the response to GH treatment in GH deficiency.

OBJECTIVE To identify factors, particularly the growth hormone (GH) provocation test result, affecting growth response to GH treatment in children with GH deficiency (GHD). SUBJECTS A total of 337 prepubertal GHD patients aged <10 years from the UK Pharmacia KIGS database (GH response to provocation test <20 mU/l). OUTCOME MEASURE Annual change in height standard deviation score (SDS) (revi...

Diagnosis of Growth Hormone Deficiency and Growth Hormone Stimulation Tests

Tests for growth hormone secretion.

Tests for growth hormone secretion SIR,-We were interested in the correspondence between Dr Addy and Professor Brook and Dr Hindmarsh on detecting organic illness through assessment of height velocity .' 2 The question, however, is academic and their arguments theoretical since, as we have recently shown, the assessment of height velocity in individuals is so imprecise as to be clinically meani...

Tests for growth hormone secretion.

Tests for growth hormone secretion SIR,-Professor Brook and Dr Hindmarsh claim that children growing at a less than 3rd centile velocity carry a 97% chance of showing an abnormality on investigation.' In a leading article in the British Medical Journal in 1986 they wrote 'If a third centile velocity is chosen for immediate action the chances of investigating a normally growing child are only 3%...